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What are the eIGA CPG-A & CPG-S?

The eIGA CPG-A and CPG-S are validated, standardized assessment tools for evaluating the activity and stage of chronic prurigo (CPG) from the perspective of the treating physician based on predefined criteria. The number of lesions is representative of the stage of the disease, while the extent of excoriations or crusts reflects scratching activity. They were originally developed for the objective assessment of CPG in clinical trials but are increasingly being used in clinical practice as a parameter to guide treatment decisions. In addition, they can be used to document the impact of treatment over time.

Validation of questionnaire

paper version: yes digital version: no

How to use the eIGA CPG-A & CPG-S

Both the eIGA CPG-A and the eIGA CPG-S should only be used by trained healthcare professionals.

The eIGA CPG-A assesses current scratching activity based on the proportion of pruritic lesions with excoriations and/or crusts. Only the proportion is assessed, not the severity of the individual scratch marks. The values range from 0 (clear) to 4 (severe activity), which corresponds to no visible to very active scratching.

The eIGA CPG-S assesses the severity of the stage based on the estimated total number of pruriginous lesions (papules, nodules, plaques, ulcers). All forms of chronic prurigo are taken into account. The estimated total number assigns the patient a stage, with values ranging from 0 (clear) to 4 (severe prurigo stage), corresponding to no or a lot of lesions.

Each grade is distinctly defined by a relevant morphological description to ensure the comparability of the eIGA CPG-A and eIGA CPG-S scores between healthcare providers and over time.

The importance of assessing the stage and activity of chronic prurigo

The eIGA CPG-S and CPG-A help physicians assess how many skin changes are present and how actively the patient is scratching. These two values provide a good indication of how severe the condition is at the moment and whether the skin is improving under treatment. The digital (electronic) version makes it easier to monitor progress over time. This in turn allows for better decisions on whether a therapy is effective.

References

Zeidler, C., Pereira, M. P., Augustin, M., Spellman, M., & Ständer, S. (2021). Investigator's Global Assessment of Chronic Prurigo: A New Instrument for Use in Clinical Trials. Acta dermato-venereologica, 101(2), adv00401. https://doi.org/10.2340/00015555-3701

Zeidler, C., Pereira, M. P., Storck, M., Suer, A. & Ständer, S. (2022). Severity stages of chronic nodular prurigo: analysis of associated itch intensity and quality of life impairment. Itch, 7(2), e61. https://doi.org/10.1097/itx.0000000000000061

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electronic Investigator Global Assessment for Chronic Prurigo Activity & Stage

eIGA CPG-A & CPG-S

Assessment of chronic prurigo made easy and quick

What are the eIGA CPG-A & CPG-S?

How to use the eIGA CPG-A & CPG-S

The following versions of the eIGA CPG-A & CPG-S are available

The importance of assessing the stage and activity of chronic prurigo

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